Conclusion
Caffeine improves short-term cognitive focus in healthy adults within 30–60 minutes of ingestion at moderate doses (40–300 mg), as demonstrated by multiple randomized controlled trials.
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Caffeine is an adenosine-receptor antagonist that increases cortical arousal and enhances attentional performance. RCTs consistently show improvements in sustained attention, reaction time, and vigilance tasks at doses between 40 mg and 300 mg, with effects peaking approximately 30–60 minutes post-ingestion. The cited systematic review (Nutrients, 2021) synthesizes this evidence across multiple trial designs and populations of healthy adults, confirming both the dose range and the temporal window for cognitive enhancement.
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