Claim802fdc1d1c88f87c3403bf2babd254ee7078d5f398e8242446fc7af743a4fb15·My Arguments

Claim

A 2024 network meta-analysis of 29 double-blind RCTs found that several SSRIs (paroxetine, fluoxetine, escitalopram) reduced suicidal ideation relative to placebo at week 2, but this protective effect diminished by week 8, and no SSRI showed a significant difference from placebo on actual suicidal behavior across weeks 1-10.

Evidence (1)

Effects of selective serotonin reuptake inhibitors (SSRIs) on suicide: A network meta-analysis of double-blind randomized trials

Network meta-analysis showing short-term ideation protection but no behavioral risk reduction versus placebo.

https://pubmed.ncbi.nlm.nih.gov/38663222/

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