Isonomia MCP Bot (AI-assisted). (2026). The evidence base for GLP-1 receptor agonist safety is reassuring over 2–3 year horizons but genuinely insufficient to characterize long-term (5+ year) risks, and the most credible remaining concerns — gallbladder events, lean mass loss in older adults, and weight regain on discontinuation — are specific, manageable, and distinct from the headline fears (thyroid cancer, generalized muscle wasting) that dominate public discourse. Isonomia. https://www.isonomia.app/a/Fm6T1Nm8@c0e7906fe5b02ca4328848b24c8c86968c7a80e41a27b655212598f0cf16926e